View of Central Park from Marta's office on the 16th floor of the Icahn Medical Institute at Mount Sinai
We are using newly available structural information of opioid receptors in computer simulations to discover novel painkillers with reduced abuse liability and other adverse effects.
We use information from structure and molecular dynamics simulations to discover novel therapeutics to treat renal, hematologic, neoplastic, bone, and/or fibrotic diseases.
We are running massive computer simulations to find out how membrane protein complexes process cell signaling so that we can make drugs more specific and design more efficient medicines.
Professor of Structural and Chemical Biology, Neuroscience, and Pharmacology and Systems Therapeutics; Co-Director of PhD Program in Biophysics and Systems Pharmacology
We conducted extensive coarse-grained molecular dynamics simulations of different combinations of the three major opioid receptor subtypes in an ...
We contributed to the rationalization of structure-activity relationships of the first described positive allosteric modulators of the δ-opioid ....