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2020 Filizola Lab

Located in New York City

View of Central Park from Marta's office on the 16th floor of the Icahn Medical Institute at Mount Sinai

Research Towards Non-Addictive Painkillers

We are using newly available structural information of opioid receptors in computer simulations to discover novel painkillers with reduced abuse liability and other adverse effects.

Development of Novel, Pure Antagonists of Beta3 Integrins

We use information from structure and molecular dynamics simulations to discover novel therapeutics to treat renal, hematologic, neoplastic, bone, and/or fibrotic diseases.

Understanding How Membrane Proteins Mediate Cellular Functions

We are running massive computer simulations to find out how membrane protein complexes process cell signaling so that we can make drugs more specific and design more efficient medicines.

We belong to the Department of Pharmacological Sciences at the Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY, USA.
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Our Team

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April 2018
MD student Jason Lee starts his summer project in the lab
October 2017
Yi's baby girl is born
September 2017
Abhijeet's paper is accepted in Nature Scientific Reports
April 2017
Xiaohu Hu joins the lab as a postdoctoral associate